Abschlussarbeiten

2019

Master

Michael Bell: Exploring mechanisms of axonal Tau sorting in human SH-SY5Y-derived and primary mouse neurons

2018

Bachelor

Michelle Scharte: Generation of spinal muscular atrophies modyfiers knockout cell lines using CRISPR/Cas9

Master

Tamas Schmidt: Characterization of STIM1 as a novel PLS3 binding partner in spinal muscular atrophy

Lea Middelmann: A new high throughput technique for the molecular diagnosis of polycystic kidney disease patients

2017

Bachelor

Charlotte Marie Johanna Dresen: Functional Analysis of Vesicle Trafficking in Spinal Muscular Atrophy

2016

Bachelor

Johanna Brecht: Characterization of microRNA processing enzyme, Drosha in Spinal Muscular Atrophy

Master

Björn Reusch: MAGED2 associated polyhydramnions and transient Bartter-like syndrome

Maximilian Thelen: Characterization of ATP Synthesis in Spinal Muscular Atrophy

2015

Master

Wiebke Rehorst: Characterization of Intercellular Communication Mechanisms at the Neusomuscular Junction in Spinal Muscular Atrophy

Nadine Rosin: Novel Insights into Molecular Mechanisms Underlying Syndromic Microcephaly

2014

Master

Inês do Carmo Gil Gonçalves: The role of SMN protein in miRNA biogenesis

Nasim Biglari: Identification of interacting partners of a modifier of spinal muscular atrophy

2013

Bachelor

Kristina Vogtmann: Promoter analysis of Akt1 and mTOR in spinal muscular atrophy

Master

Janine Milbradt: Cytoskeleton modifiers in bone development

Eva Janzen: Identification of Binding Partners of Plastin 3, a Modifier of Spinal Muscular Atrophy

2012

Master

Mario Paterno: In vitro und in vivo Charakterisierung des Histon-Deacetylase-Inhibitors JNJ-26481585 als potenzielles Therapeutikum für die autosomal rezessive proximale spinale Muskelatrophie (SMA)

2011

Bachelor

Stefanie Rösler: Molecular basis of inheritable cone-rod dystrophy associated with myopia magna; Identification and characterization of a novel gene defect

Master

Lilian Martinez: Molecular analysis of the OCLN gene in patients with spinal muscular atrophy and brain atrophy

Rainer Akkermann: Peroxisome proliferator-activated receptor δ expression in myeloid cells mediates sex differences in recovery from paralysis in experimental autoimmune encephalomyelitis

2010

Master

Immanuel Weber: Search for potential modifiers in Spinal Muscular Atrophy patients

Guido Neidhardt: The epigenetic regulation of glutamate transporters in malignant glioma

2009

Bachelor

Henrike Kristen: Der Einfluss des HDAC-Inhibitors M344 auf das Spleißen von SMN2 in Smn-/-, Smn+/+ und Sfrs10- defizienten murinen embryonalen Fibroblasten

Master

Agata Nasilowska: The molecular role of histone deacetylase (HDAC) isozymes in glioma progression and therapy

Diplom

Stephanie Friedrichs: Generierung von murinen induziert pluripotenten Stammzellen und deren Differenzierung in Motoneurone

Katharina Keupp: Genetische und funktionelle Charakterisierung autosomal rezessiver Taubheitsgene

Abschlussarbeiten 2004–2008
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