Master

Lena Kluge: Virus-based knockdown of TAU isoforms in iPSC-derived neurons as a gene therapy approach for Alzheimer´s disease and related dementia syndromes

Felix Langerscheidt: Lentiviral production and expression of polymerase-γ, associated proteins and regulators of mitochondrial biogenesis

Timo Lange: Cell-type specific atlas of methylation - correlating scEMseq references for methylation deconvolution and expression profiles from scRNA in human tissue

Master

Jennifer Oly: Treatment approaches for the neurogenetic Alpers syndrome and other POLG-related mitochondriopathies using two neuronal cell models and patient fibroblasts

Lisa Wolff: Study of the SMA protective modifiers PLS3 and CHP1 in neurodegenerative disorders

Bachelor

Magdalena Krubner: Role of miRNAs in Spinal Muscular Atrophy

Master

Michael Bell: Exploring mechanisms of axonal Tau sorting in human SH-SY5Y-derived and primary mouse neurons

Tamas Schmidt: Characterization of STIM1 as a novel PLS3 binding partner in spinal muscular atrophy

Bachelor

Michelle Scharte: Generation of spinal muscular atrophies modyfiers knockout cell lines using CRISPR/Cas9

Master

Lea Middelmann: A new high throughput technique for the molecular diagnosis of polycystic kidney disease patients

Bachelor

Charlotte Marie Johanna Dresen: Functional Analysis of Vesicle Trafficking in Spinal Muscular Atrophy

Bachelor

Johanna Brecht: Characterization of microRNA processing enzyme, Drosha in Spinal Muscular Atrophy

Master

Björn Reusch: MAGED2 associated polyhydramnions and transient Bartter-like syndrome

Maximilian Thelen: Characterization of ATP Synthesis in Spinal Muscular Atrophy

Master

Wiebke Rehorst: Characterization of Intercellular Communication Mechanisms at the Neusomuscular Junction in Spinal Muscular Atrophy

Nadine Rosin: Novel Insights into Molecular Mechanisms Underlying Syndromic Microcephaly

Master

Inês do Carmo Gil Gonçalves: The role of SMN protein in miRNA biogenesis

Nasim Biglari: Identification of interacting partners of a modifier of spinal muscular atrophy

Bachelor

Kristina Vogtmann: Promoter analysis of Akt1 and mTOR in spinal muscular atrophy

Master

Janine Milbradt: Cytoskeleton modifiers in bone development

Eva Janzen: Identification of Binding Partners of Plastin 3, a Modifier of Spinal Muscular Atrophy

Master

Mario Paterno: In vitro und in vivo Charakterisierung des Histon-Deacetylase-Inhibitors JNJ-26481585 als potenzielles Therapeutikum für die autosomal rezessive proximale spinale Muskelatrophie (SMA)

Bachelor

Stefanie Rösler: Molecular basis of inheritable cone-rod dystrophy associated with myopia magna; Identification and characterization of a novel gene defect

Master

Lilian Martinez: Molecular analysis of the OCLN gene in patients with spinal muscular atrophy and brain atrophy

Rainer Akkermann: Peroxisome proliferator-activated receptor δ expression in myeloid cells mediates sex differences in recovery from paralysis in experimental autoimmune encephalomyelitis

Master

Immanuel Weber: Search for potential modifiers in Spinal Muscular Atrophy patients

Guido Neidhardt: The epigenetic regulation of glutamate transporters in malignant glioma

Bachelor

Henrike Kristen: Der Einfluss des HDAC-Inhibitors M344 auf das Spleißen von SMN2 in Smn-/-, Smn+/+ und Sfrs10- defizienten murinen embryonalen Fibroblasten

Master

Agata Nasilowska: The molecular role of histone deacetylase (HDAC) isozymes in glioma progression and therapy

Diplom

Stephanie Friedrichs: Generierung von murinen induziert pluripotenten Stammzellen und deren Differenzierung in Motoneurone

Katharina Keupp: Genetische und funktionelle Charakterisierung autosomal rezessiver Taubheitsgene